Fatal transfusion reaction due to the Kell factor.
نویسندگان
چکیده
منابع مشابه
[A hemolytic transfusion reaction due to Anti-Ku antibody in a patient with Knull phenotype: the first case in Korea].
Knull phenotype completely lacks all Kell system antigens. Anti-Ku antibody is seen in immunized persons with Knull phenotype by transfusion or pregnancy. It can cause a fatal hemolytic transfusion reaction. A 66-yr-old male patient with liver cirrhosis visited emergency center due to acute bleeding. The patient was at hypovolemic shock status: his blood pressure was 80/50 mmHg, pulse rate was ...
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INTRODUCTION Kell antigen is highly immunogenic and is the common cause of antibody production in mismatched blood transfusions, haemolytic transfusion reaction (HTR) and maternal alloimmunization, which causes severe anaemia in neonates. The aim of this study is to determine the prevalence and ethnic variation of the Kell phenotype among pregnant women in Sokoto, Nigeria. METHODS Kell antige...
متن کاملPrevalence of Alloantibodies and Autoantibodies in Transfusion Dependent Thalassemia Patients
Background: The development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. Also, Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. We studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in Ilam province...
متن کاملAn easy and efficient strategy for KEL genotyping in a multiethnic population
BACKGROUND The Kell blood group system expresses high and low frequency antigens with the most important in relation to transfusion including the antithetic KEL1 and KEL2; KEL3 and KEL4; KEL6 and KEL7 antigens. Kell is a clinically relevant system, as it is highly immunogenic and anti-KEL antibodies are associated with hemolytic transfusion reactions and hemolytic disease of the fetus and newbo...
متن کاملبررسی آلوایمیونیزاسیون در بیماران مولتی ترانس فیوز (تالاسمی) مراجعهکننده به بیمارستان حضرت علی اصغر(ع) تهران در سال 84-1383
Background and Aim: Life long red blood transfusion remains the main treatment for severe thalassemia. The development of anti–RBC antibodies can significantly complicate transfusion therapy. Microtyping (Gel method) is the method which is recommended at present for screening and typing of antibodies. The aim of this study is to screen antibodies by Gel method and to replace the tube method...
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ورودعنوان ژورنال:
- Blood
دوره 8 11 شماره
صفحات -
تاریخ انتشار 1953